Miniature probe for all-optical double gradient-index lenses photoacoustic microscopy

A miniature all-optical photoacoustic imaging probe

A miniature (250 μm outer diameter) photoacoustic probe for endoscopic applications has been developed. It comprises a single delivery optical fibre with a transparent Fabry Perot (FP) ultrasound sensor at its distal end. The fabrication of the sensor was achieved by depositing a thin film multilayer structure comprising a polymer spacer sandwiched between a pair of dichroic dielectric mirrors ...

All-optical photoacoustic microscopy

Three-dimensional photoacoustic microscopy (PAM) has gained considerable attention within the biomedical imaging community during the past decade. Detecting laser-induced photoacoustic waves by optical sensing techniques facilitates the idea of all-optical PAM (AOPAM), which is of particular interest as it provides unique advantages for achieving high spatial resolution using miniaturized embod...

Double-illumination photoacoustic microscopy.

Recent developments of optical-resolution photoacoustic microscopy (OR-PAM) have improved its spatial resolution and imaging speed. However, the penetration depth of OR-PAM is still limited to ~1 mm in tissue, owing to the strong tissue scattering. Here, we have developed double-illumination PAM (DI-PAM), which illuminates the sample from both top and bottom sides simultaneously. Through phanto...

Optical-Resolution Photoacoustic Microscopy

Pure optical photoacoustic microscopy

The concept of pure optical photoacoustic microscopy(POPAM) was proposed based on optical rastering of a focused excitation beam and optically sensing the photoacoustic signal using a microring resonator fabricated by a nanoimprinting technique. After the refinements of the microring's working wavelength and in the resonator structure and mold fabrication, an ultrahigh Q factor of 3.0×10(5) was...